Thursday, November 12, 2015

Newly Published Reports on Oncology

bannerMicroRNAs involved with hepatocellular carcinoma (Review)
Bijing Mao, Ge Wang

Role of the LKB1/AMPK pathway in tumor invasion and metastasis of cancer cells (Review)
Nianshuang Li, Deqiang Huang, Nonghua Lu, Lingyu Luo

Targeting cryptic epitope with modified antigen coupled to the surface of liposomes induces strong antitumor CD8 T-cell immune responses in vivo
Yutaka Horiuchi, Akira Takagi, Tetsuya Uchida, Toshitaka Akatsuka

Surgical cytoreduction of the primary tumor reduces metastatic progression in a mouse model of prostate cancer
Federico F. Cifuentes, Rodrigo H. Valenzuela, Héctor R. Contreras, Enrique A. Castellón

Trichosanthin suppresses the proliferation of glioma cells by inhibiting LGR5 expression and the Wnt/β-catenin signaling pathway
Junjie Miao, Yilin Jiang, Dongliang Wang, Jingru Zhou, Cungang Fan, Feng Jiao, Bo Liu, Jun Zhang, Yangshuo Wang, Qingjun Zhang

CMTM8 inhibits the carcinogenesis and progression of bladder cancer
Denghui Gao, Hao Hu, Ying Wang, Weidong Yu, Jianhua Zhou, Xiaofeng Wang, Weiping Wang, Chunyan Zhou, Kexin Xu

Lapatinib enhances trastuzumab-mediated antibody-dependent cellular cytotoxicity via upregulation of HER2 in malignant mesothelioma cells
Riki Okita, Katsuhiko Shimizu, Yuji Nojima, Takuro Yukawa, Ai Maeda, Shinsuke Saisho, Masao Nakata

Phloretin induces apoptosis of non-small cell lung carcinoma A549 cells via JNK1/2 and p38 MAPK pathways
Jie Min, Xu Li, Kenan Huang, Hua Tang, Xinyu Ding, Chen Qi, Xiong Qin, Zhifei Xu

A CXCR4 antagonist leads to tumor suppression by activation of immune cells in a leukemia-induced microenvironment
A-Reum Han, Ji Yoon Lee, Hee-Je Kim, Woo-Sung Min, Gyeongsin Park, Se-Hoon Kim

Benzyl butyl phthalate increases the chemoresistance to doxorubicin/cyclophosphamide by increasing breast cancer-associated dendritic cell-derived CXCL1/GROα and S100A8/A9
Ya-Ling Hsu, Jen-Yu Hung, Eing-Mei Tsai, Cheng-Ying Wu, Ya-Wen Ho, Shu-Fang Jian, Meng-Chi Yen, Wei-An Chang, Ming-Feng Hou, Po-Lin Kuo

Isothiocyanates inhibit the invasion and migration of C6 glioma cells by blocking FAK/JNK-mediated MMP-9 expression
Chang-Su Lee, Hyun-Ji Cho, Yun-Jeong Jeong, Jae-Moon Shin, Kwan-Kyu Park, Yoon-Yub Park, Young-Seuk Bae, Il-Kyung Chung, Mihyun Kim, Cheorl-Ho Kim, Fansi Jin, Hyeun-Wook Chang, Young-Chae Chang

Antitumor effect of COOH-terminal polypeptide of human TERT is associated with the declined expression of hTERT and NF-κB p65 in HeLa cells
Xian Wu, Jiasheng Chen, Ying Cao, Baoping Xie, Hongwei Li, Pingzheng Zhou, Yuchang Qiu, Jianxin Pang

USP14 activation promotes tumor progression in hepatocellular carcinoma
Gang Huang, Limei Li, Weiping Zhou

Early and delayed intervention with Rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice
Jagan M.R. Patlolla, Levy Kopelovich, Li Qian, Yuting Zhang, Gaurav Kumar, Venkateshwar Madka, Altaf Mohammed, Laura Biddick, Michael Sadeghi, Stan Lightfoot, Chinthalapally V. Rao

SIRT1 downregulation enhances chemosensitivity and survival of adult T-cell leukemia-lymphoma cells by reducing DNA double-strand repair
Liang Li, Shiguang Ye, Meng Yang, Wenlei Yu, Zhuoyi Fan, Hong Zhang, Jiong Hu, Aibin Liang, Wenjun Zhang

OCT4B1 promotes cell growth, migration and invasion suppressing sensitivity to οxaliplatin in colon cancer
Kun-Ming Wen, Gui-Hai Zhang, Jiang Li, Zheng-Quan Chen, Yi-Lin Cheng, Xuan Su, Qing-Liang Zeng

ABL-N may induce apoptosis of human prostate cancer cells through suppression of KLF5, ICAM-1 and Stat5b, and upregulation of Bax/Bcl-2 ratio: An in vitro and in vivo study
Yanping Zhang, Kailong Liu, Yong Zhang, Jinchun Qi, Baosai Lu, Chongjun Shi, Yuewei Yin, Wenqing Cai, Wei Li

MicroRNA-92b promotes tumor growth and activation of NF-κB signaling via regulation of NLK in oral squamous cell carcinoma
Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng

High mobility group box 1-mediated autophagy promotes neuroblastoma cell chemoresistance
Li Wang, Huiping Zhang, Min Sun, Zhanghua Yin, Jihong Qian

Ultrasound-targeted microbubble destruction-mediated downregulation of CD133 inhibits epithelial-mesenchymal transition, stemness and migratory ability of liver cancer stem cells
Yan-Min Liu, Xuan-Fei Li, Hao Liu, Xiao-Ling Wu

Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies
Takayuki Fujimori, Kiyohito Kato, Shintaro Fujihara, Hisakazu Iwama, Takuma Yamashita, Kiyoyuki Kobayashi, Hideki Kamada, Asahiro Morishita, Hideki Kobara, Hirohito Mori, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki

Malignant transformation of host stromal fibroblasts derived from the bone marrow traced in a dual-color fluorescence xenograft tumor model
Xingliang Dai, Hua Chen, Yanming Chen, Jinding Wu, Haiyang Wang, Jia Shi, Xifeng Fei, Zhimin Wang, Aidong Wang, Jun Dong, Qing Lan, Qiang Huang

RANKL/RANK interaction promotes the growth of cervical cancer cells by strengthening the dialogue between cervical cancer cells and regulation of IL-8 secretion
Wen-Qing Shang, Hui Li, Li-Bing Liu, Kai-Kai Chang, Jia‑Jun Yu, Feng Xie, Ming-Qing Li, Jin-Jin Yu

Upregulation of BTG1 enhances the radiation sensitivity of human breast cancer in vitro and in vivo
Ran Zhu, Wei Li, Yan Xu, Jianmei Wan, Zengli Zhang

Berberine-induced anticancer activities in FaDu head and neck squamous cell carcinoma cells
Yo-Seob Seo, Min-Ji Yim, Bok-Hee Kim, Kyung-Rok Kang, Sook-Young Lee, Ji-Su Oh, Jae-Seek You, Su-Gwan Kim, Sang-Joun Yu, Gyeong-Je Lee, Do Kyung Kim, Chun Sung Kim, Jin-Soo Kim, Jae-Sung Kim

Polyphenol mixtures of Euphorbia supina the inhibit invasion and metastasis of highly metastatic breast cancer MDA-MB-231 cells
Young Shin Ko, Won Sup Lee, Young Nak Joo, Yung Hyun Choi, Gon Sup Kim, Jin-Myung Jung, Chung Ho Ryu, Sung Chul Shin, Hye Jung Kim

β-asarone inhibits gastric cancer cell proliferation
Jian Wu, Xing-Xing Zhang, Qing-Min Sun, Min Chen, Sheng‑Lin Liu, Xiang Zhang, Jin-Yong Zhou, Xi Zou

Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis
Ye Xu, Chunyan Wang, Jing Su, Qi Xie, Liwei Ma, Linchuan Zeng, Yang Yu, Shibing Liu, Songyan Li, Zhixin Li, Liankun Sun

Frizzled2 mediates the migration and invasion of human oral squamous cell carcinoma cells through the regulation of the signal transducer and activator of transcription-3 signaling pathway
Enjiao Zhang, Zhenning Li, Zhongfei Xu, Weiyi Duan, Changfu Sun, Li Lu

Tetraspanin 1 is involved in survival, proliferation and carcinogenesis of pancreatic cancer
Feng-Qiang Hou, Xi-Feng Lei, Jian-Long Yao, Yi-Jin Wang, Wei Zhang

Downregulation of NOB1 inhibits proliferation and promotes apoptosis in human oral squamous cell carcinoma
Jirong Yin, Juncheng Wang, Yi Jiang, Lili Wang, Hao Wu, Hongchen Liu

miR-130a regulates macrophage polarization and is associated with non-small cell lung cancer
Lin Lin, Haibo Lin, Lin Wang, Bin Wang, Xuezhi Hao, Yuankai Shi

Screening and verification of proteins that interact with HSPC238
Jia-Yu Tan, Jing-Lin Chen, Xiang Huang, Chun-Lei Yuan

MicroRNA-205 suppresses the growth of adrenocortical carcinoma SW-13 cells via targeting Bcl-2
Yigao Wu, Wei Wang, Weilie Hu, Wenqing Xu, Ge Xiao, Qiwei Nie, Keyu Ouyang, Shuai Chen

Downregulation of Notch1 induces apoptosis and inhibits cell proliferation and metastasis in laryngeal squamous cell carcinoma
Meng-Yuan Dai, Fang Fang, You Zou, Xing Yi, Yong-Jun Ding, Chen Chen, Ze-Zhang Tao, Shi-Ming Chen

Autocrine interferon-γ may affect malignant behavior and sensitivity to tamoxifen of MCF-7 via estrogen receptor β subtype
Xiu Long Niu, Yue Wang, Zhi Yao, Hongjie Duan, Zhijun Li, Wenxing Liu, Hongjian Zhang, Wei Min Deng

Argininosuccinate lyase is a potential therapeutic target in breast cancer
Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu‑Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai

Silencing β-linked N-acetylglucosamine transferase induces apoptosis in human gastric cancer cells through PUMA and caspase-3 pathways
Ti Wen, Kezuo Hou, Zhi Li, Lu Li, Hanjie Yu, Yunpeng Liu, Yangguang Li, Zhinan Yin

Autophagy in human skin squamous cell carcinoma: Inhibition by 3-MA enhances the effect of 5-FU-induced chemotherapy sensitivity
Lili Zhang, Jie Zhang, Li Chen, Jianli Wang

RSK4 knockdown promotes proliferation, migration and metastasis of human breast adenocarcinoma cells
Jia Zhu, Qiu-Yun Li, Jian-Lun Liu, Wei Wei, Hua-Wei Yang, Wei Tang

Combined expression of aldehyde dehydrogenase 1A1 and β-catenin is associated with lymph node metastasis and poor survival in breast cancer patients following cyclophosphamide treatment
Mingli Sun, Haishan Zhao, Qinghuan Xiao, Zhaojin Yu, Zhiguo Song, Weifan Yao, Hongtao Tang, Shu Guan, Feng Jin, Minjie Wei

Loss of function of Notch1 identifies a poor prognosis group of early stage hepatocellular carcinoma following hepatectomy
Jian Liu, Jing-Feng Liu, Kui Wang, Zhen-Lin Yan, Xu-Ying Wan, Ai-Min Huang, Yi-Zhou Wang, Jun Li, Yong Xia, Le-Hua Shi, Bing-Hua Jiao, Yongjie Zhang, Feng Shen

Knockdown of Cul4A increases chemosensitivity to gemcitabine through upregulation of TGFBI in lung cancer cells
Ming‑Szu Hung, I‑Chuan Chen, Liang You, David M. Jablons, Ya‑Chin Li, Jian‑Hua Mao, Zhidong Xu, Meng‑Jer Hsieh, Yu‑Ching Lin, Cheng‑Ta Yang, Shih‑Tung Liu, Ying‑Huang Tsai

Overall survival with and without laryngeal function preservation in 580 patients with hypopharyngeal squamous cell carcinoma
Jieyu Zhou, Yongmei Li, Dongmin Wei, Ye Qian, Wenming Li, Dayu Liu, Guojun Li, Xinliang Pan, Dapeng Lei

Antiproliferation effect of evodiamine in human colon cancer cells is associated with IGF-1/HIF-1α downregulation
Jun Huang, Zhen-Hua Chen, Chun-Mei Ren, Dong-Xu Wang, Shuang‑Xue Yuan, Qiu-Xiang Wu, Qian-Zhao Chen, Yu-Hua Zeng, Ying Shao, Yang Li, Ke Wu, Yu Yu, Wen-Juan Sun, Bai-Cheng He

Long non-coding RNA growth arrest-specific transcript 5 is involved in ovarian cancer cell apoptosis through the mitochondria-mediated apoptosis pathway
Jiayin Gao, Meimei Liu, Yiting Zou, Min Mao, Tingting Shen, Chen Zhang, Shasha Song, Meiling Sun, Song Zhang, Beidi Wang, Daling Zhu, Peiling Li

Autophagy is upregulated during colorectal carcinogenesis, and in DNA microsatellite stable carcinomas
Paola Sena, Francesco Mariani, Stefano Mancini, Marta Benincasa, Giulia Magnani, Monica Pedroni, Carla Palumbo, Luca Roncucci

Expression of ADAM12 is regulated by E2F1 in small cell lung cancer
Zunling Li, Yaopeng Wang, Lijun Kong, Zhen Yue, Ying Ma, Xufang Chen

Mitochondrial dysfunction rather than mtDNA sequence mutation is responsible for the multi-drug resistance of small cell lung cancer
Lijie Ma, Ruixuan Wang, Hongtao Duan, Yandong Nan, Qingwei Wang, Faguang Jin

Differences in urinary proteins related to surgical margin status after radical prostatectomy
Zbynek Heger, Petr Michalek, Roman Guran, Natalia Cernei, Katerina Duskova, Stepan Vesely, Jiri Anyz, Olga Stepankova, Ondrej Zitka, Vojtech Adam, Rene Kizek

Caveolin-1 mediates chemoresistance in cisplatin‑resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-κB pathway
Wei Zou, Xiangdong Ma, Wei Hua, Biliang Chen, Guoqing Cai

LMP1 promotes nasal NK/T-cell lymphoma cell function by eIF4E via NF-κB pathway
Lu Sun, Yu Zhao, Huaiyin Shi, Chao Ma, Lixin Wei

miR-154 targeting ZEB2 in hepatocellular carcinoma functions as a potential tumor suppressor
Xiaoli Pang, Kexin Huang, Qianqian Zhang, Yujiao Zhang, Junqi Niu

The role of Pyk2 in the CCR7-mediated regulation of metastasis and viability in squamous cell carcinoma of the head and neck cells in vivo and in vitro
Yang Yue, Zhen-Ning Li, Qi-Gen Fang, Xu Zhang, Liang‑Liang Yang, Chang-Fu Sun, Fa-Yu Liu

PBK/TOPK mediates promyelocyte proliferation via Nrf2-regulated cell cycle progression and apoptosis
Yuhong Liu, Hui Liu, Huiqin Cao, Bin Song, Wen Zhang, Wanggang Zhang

Overexpression of osteopontin promotes resistance to cisplatin treatment in HCC
Kun Ding, Lu Fan, Shijun Chen, Yanna Wang, Haifeng Yu, Yanni Sun, Jiguang Yu, Li Wang, Xiangzhong Liu, Youde Liu

The flavonoid p-hydroxycinnamic acid exhibits anticancer effects in human pancreatic cancer MIA PaCa-2 cells in vitro: Comparison with gemcitabine
Masayoshi Yamaguchi, Tomiyasu Murata, Bassel F. El‑Rayes, Mamoru Shoji

Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway
Lichuan Wu, Liangxia Guo, Yuehui Liang, Xu Liu, Lihe Jiang, Lisheng Wang

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